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Search Results for " human hsc "

7

Compounds

Cat No. Product Name Synonyms Targets
T9230 KM 91104 ATPase
KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2.
T1606 Fasudil HA-1077,AT877 ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy
Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T3060 Fasudil hydrochloride Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877 ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T69241 MEISi-1
MEISi-1 is a novel MEIS inhibitor (MEISi), significantly inhibiting MEIS-luciferase reporters in vitro and inducing murine (LSKCD34low cells) and human (CD34+, CD133+, and ALDHhi cells) HSC self-renewal ex vivo.
TN2177 Sanggenol L c-Myc , NF-κB
Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apoptosis via caspase activation and inhibition of NF-κB/IκBα± ph...
T81951 Lanosta-7,9(11),24-trien-3α-hydroxy-26-oic acid
Ganoderic acid 24, chemically designated as lanosta-7,9(11),24-trien-3α-hydroxy-26-oic acid, exhibits significant cytotoxicity against various cancer cell lines, including human lung cancer cells CH27, melanoma cells M21...
T35426 β-Defensin-1 (human) (trifluoroacetate salt)
β-Defensin-1 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth ofB. adolescentis,L. acidophilus...
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